Subsidiaries of the Registrant

ZIVO Bioscience, Inc. has the following Subsidiaries:

Jurisdiction of Incorporation or Organization

Health Enhancement Corporation

Nevada Corporation

HEPI Pharmaceuticals, Inc.

Nevada Corporation

Wellmetrix, LLC (fka WellMetris, LLC)

Delaware limited liability company

Zivo Biologic, Inc.

Delaware corporation

Zivo Bioscience, LLC

Florida limited liability company